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ScoliScore Questions

ScoliScore is a Prognostic Genetic Test that can predict the progression of scoliosis in the early stages of diagnosis and development. This test virtually eliminates the traditional 'wait and see' method often prescribed by orthopedic specialists for patients with curves that are lower that 25 degrees.


What are the results of the ScoliScore™ Test?

The ScoliScore Test provides a Curve Progression Score result that assigns a numerical value to the likelihood of a scoliotic curve progression. This result corresponds to the likelihood of mild, moderate, or severe curves—among adolescents between the ages of 9-13 years. This test adds information beyond the traditional factors your physician considers when evaluating the patient.

It is important to note that a Low Curve Progression Score result does not mean that there is no chance that an Adolescent will have some curve progression. Instead, the Curve Progression Score provides information about the likelihood of curve progression—it cannot determine with 100% certainty that there will be no curve progression.

How long does it take to get Scoliscore™ results?

It will typically take 7-10 days from the date the DNA sample is received by Axial Biotech Laboratories for the results to be available. The ScoliScore Test report form is sent directly to the physician who ordered the test. Your physician will explain the test results to you.

What type of sample is needed for ScoliScore™?

The ScoliScore Test process is performed using a very small sample of DNA collected from a saliva sample during a physicians' office visit. This means that you will NOT need to have blood drawn in order to have the ScoliScore Test. The physician or nurse will ask you to spit into a plastic tube which is part of a special kit used to submit the saliva sample to the Axial Biotech Laboratory for analysis.

Is the ScoliScore™ Test right for me?

If your child has recently been diagnosed with Adolescent Idiopathic Scoliosis and have not yet begun a treatment regimen, the ScoliScore Test may be appropriate for you. However, the decision to use the ScoliScore Test is one that you and your doctor should discuss and make together.

What are the benefits of the ScoliScore™ Test?

The ScoliScore Test provides a Curve Progression Score™ result that assigns a numerical value of the likelihood of AIS curve progression that is specific to each patient. This result corresponds to the likelihood of mild, moderate, or severe curves—among adolescents between the ages of 9-13 years. The test report delivers information for both physicians and patients with AIS that may improve their confidence that treatment planning will be based on an understanding of each individual patient's disease characteristics.

When should the ScoliScore™ Test be used?

The ScoliScore Test is appropriate for adolescents between the ages of 9-13 years who have recently been diagnosed with Adolescent Idiopathic Scoliosis. The ScoliScore Test is performed on a saliva sample obtained in a physician's office. Ideally the test is performed when scoliosis is first diagnosed. The ScoliScore Test can help with discussions to determine the most appropriate treatment for each individual patient.

It is important to know that currently the ScoliScore Test is only for patients diagnosed with Adolescent Idiopathic Scoliosis (AIS). If you were diagnosed with Scoliosis several years ago, and do not know the type of Scoliosis you have been diagnosed with, check with your doctor and ask whether ScoliScore would be appropriate for you.

How does the ScoliScore™ Test work?

The ScoliScore AIS Prognostic Test analyzes DNA extracted from a saliva sample and compares genetic markers that have been linked in clinical trials to the risk of spinal curve progression. The more genetic markers that there are, which indicate a high risk of curve progression, the higher the score will be. The results of the analysis are then put into a mathematical equation to convert those measures into the ScoliScore Curve Progression Score. The score ranges from 1-200. This range has then been further broken into categories: Low, Medium, High, that refer to the likely risk of curve progression among adolescents with mild scoliosis between the ages of between the ages of 9-13 years.

What is the ScoliScore™ AIS Prognostic Test?

The ScoliScore™ AIS Prognostic Test is a clinically validated, multi-marker test that provides a qualitative and quantitative assessment of the likelihood of spinal curve progression for patients who have been diagnosed with AIS. The ScoliScore Test is leading the way to individualized scoliosis treatment by providing patient-specific information that is used to help health care providers optimize treatment plans.